A few years ago I took an all-night drive down the Pacific Coast Highway. The only rule was that I had to be back at the San Jose airport by eight in the morning. So I gassed up the rental, picked up a couple of Red Bulls, and started driving.
By day, it's one of the most scenic highways. By night, it feels like another world. Once you get below Carmel, there is no light pollution, and the stars are big and bright. As it happened, the moon illuminated the road, and my eyes got used to it, was more comfortable than daytime driving. I would stop at pullouts overlooking the coast and take long exposure images like this one at ten seconds.
Also, the lighthouses are fun to look at as they cast their rotating beams in the fog and low clouds. The one in the distance is Point Sur Lightstation. I made it down to San Simeon and turned the car around. It was a long drive back, but the sense of adventure (and Red Bull) kept me going. I made it back in time to grab my bags from the hotel and catch my flight home. And lucky for me, it was the pilot's turn to drive, so I slept all the way back to Florida.